Developmental Pathways, Plasticity and Neural Regulation of Pediatric High-Grade Glioma

Time: 12:45 pm
day: Day One

Details:

  • The architecture of pediatric high-grade gliomas resembles normal
    development
  • Histone 3 mutant gliomas (K27M and G34R/V) have distinct developmental origins
  • Intra-tumoral hierarchy and plasticity is tumor-type specific
  • Targeting lineage specific cancer cell states represents new treatment
    approach

Speakers: