John Higgins

Managing Director Brain Tumor Investment Fund

John Higgins is Managing Director at the Brain Tumor Investment Fund. John’s career spans 30 years in biopharma commercialization and business development, progressing in roles of increasing responsibility within both large and emerging companies. Prior to BTIF, John served as VP Commercial and Corporate Development at Istari Oncology, a clinical-stage company formed to develop and commercialize an investigational immune activator for glioblastoma and other solid tumors. John was integral in Istari’s Series B raise of over $40M, as well as starting the business development function and creating a significant number of business relationships for the company. Prior to that, John served as President and General Manager of ProStrakan Inc., (now Kyowa Kirin) leading the transformation of that oncology business into a profit-contributor. John’s range of experience also includes AstraZeneca, Baxter Healthcare, NicOx Inc. and Cytogen. John’s role in BTIF is to raise philanthropic capital and leverage the National Brain Tumor Society’s (NBTS) expertise to identify and purposefully invest in emerging biotechnology, pharmaceutical, and medical device companies developing new treatments and diagnostics for brain tumors. John leads the end-to-end process, including identification, outreach, due diligence and investment with the goal to fuel the development of new and promising brain tumor treatments that might otherwise be stalled by funding gaps. John received his B.A. from Villanova University.

Seminars

Wednesday 18th February 2026
Investor Perspectives Panel Discussion: What Drives Philanthropic & Venture Investment in the Challenging Glioblastoma Landscape?
4:30 pm
  • Discussing key milestones, translatable models and biomarkers that are prioritized by investors to mitigate the high-risk nature of GBM drug development
  • Exploring how philanthropic funds can de-risk early-stage assets for later VC investment, highlighting overlapping interests and divergencies and how to create a compelling value-proposition for both
  • Managing venture philanthropy co-investments, public-private partnerships, and strategic alliances, that are essential for accelerating the development of transformative therapies in this challenging field
John Higgins, speaking at the 7th Glioblastoma Drug Development Summit