Ulrike Gerdemann
Principal Investigator & Physician Scientist Dana-Farber Cancer Institute
Ulrike is a translational researcher with expertise in adoptive T-cell therapy and an attending physician in paediatric Hematology-Oncolog, most recently serving as PI on Kite/Gilead’s CAR-T trial in Glioblastoma
Seminars
Wednesday 18th February 2026
Exploring Next-Generation CAR-T Treatments for Glioblastomas to Overcome the Tumor Microenvironment & Ensure Efficacy
8:30 am
- Reviewing critical lessons from past CAR-T clinical trials in GBM to highlight efficacy barriers caused by the tumor microenvironment
- Detailing next-generation CAR-T strategies designed to resist suppression through the knockdown of upstream receptors that sense TME signals to enhance CAR-T survival in the brain
- Discussing how these novel approaches can overcome GBM’s immune resistant phenotype and achieve durable and efficacious tumour clearance
