Harnessing Tumor-Treating Fields to Modulate the Tumor Microenvironment in Glioblastoma
Time: 11:00 am
day: Workshop D
Details:
This workshop will explore the transformative potential of TumorTreating Fields in manipulating the tumor microenvironment in glioblastoma. Experts will discuss the biophysical effects of TTFields, their impact on myeloid suppressor cells, and strategies for selecting effective payloads to enhance TME modulation.
Key Discussion Points:
- Mechanisms and Effects of Tumor-Treating Fields: Review the biological and biophysical impacts of TTFields, including their role in disrupting tumor cell proliferation, DNA repair, and cellular permeability, as well as their broader effects on the TME
- Impact on Myeloid Suppressor Cells: Explore how T TFields influence myeloid-derived suppressor cells within the TME, including their potential to alter the immune landscape and enhance therapeutic efficacy
- Optimizing Payload Delivery to Enhance TME Modulation: Discuss strategies for selecting and delivering effective payloads to complement TTFields, focusing on approaches to improve TME targeting and therapeutic outcomes
