Exclusive Modulation of the Glioma TME with InC01, InCephalo’s Compartment Locked IL-12
Time: 11:45 am
day: Conference Day 1
Details:
- InCephalo’s compartment lock (C-Lock) technology enables high local CNS levels at minimal systemic exposure for antibodies or Fc-fusion constructs
- Preclinical data on the development of InC01, a C-Locked IL-12-based biologic and proof of concept data in relevant murine and human ex vivo models will be presented
- InC01 shows excellent tolerability, synergizes not only with immune checkpoint blockade but also with standard of care radio and chemotherapy and triggers proinflammatory repolarization in human GBM explants
